hrp0095rfc1.2 | Thyroid | ESPE2022

Secondary thyroid carcinoma in survivors of childhood cancer: a need to revise current screening recommendations

Atlas Gabby , Farrell Stephen , Zacharin Margaret

Thyroid cancer is the most common secondary malignancy for survivors of childhood cancer, with radiation exposure before age 18 being the most significant risk factor. Current guidelines from the Children’s Oncology Group recommend yearly physical examination to palpate for thyroid nodules. Whilst other societies recommend periodic thyroid ultrasound, further evaluation with fine needle aspirate is typically not considered for nodules less than 10mm in diameter. We descr...

hrp0097p1-392 | Thyroid | ESPE2023

A case series of multinodular goitres associated with tumour predisposition syndromes

Angley Eleanor , Farrell Stephen , Zacharin Margaret

Thyroid nodular disease, either multinodular goitre (MNG) or solitary nodule, carries a higher malignancy risk in paediatric patients compared to adults requiring closer monitoring and investigation. We present a case series of patients with multinodular goitre who were confirmed to have tumour predisposition syndromes. Eight patients (six female) with MNG were identified using electronic medical records, based on presence of MNG and/or previous genetic testing confirming eith...